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Email: aes31@case.edu

 

Avery  E.  Sears

Entering Class: 2013
PhD Program: Pharmacology
Advisor: Krzysztof Palczewski, PhD
Laboratory: W-317

Undergraduate Institution: Case Western Reserve University
Hometown: Cleveland, OH.

Research Interests: My research investigates the mechanisms behind retinoid metabolism in the retina, specifically how the visual chromophore, 11-cis¬-retinol, is produced and transported.

About me:

Comment about the MSTP program:

Featured Publication:

Golczak M, Sears AE, Kiser PD, Palczewski K. LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3. Nat Chem Biol. 2015 Jan;11(1):26-32. doi: 10.1038/nchembio.1687. Epub 2014 Nov 10. PubMed PMID: 25383759; PubMed Central PMCID: PMC4270908.

Additional Publications:

Golczak, M., Kiser, P.D., Sears, A.E., Palczewski, K. 2012. Structural basis for the acyltransferase activity of lecithin: retinol acyltransferase. Journal of Biological Chemistry. 287(28):23790-807.

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